Nobody's knows or cares to. Nobody sees the pain seeping through your pores. A face so plain yet shows the worst pain that no one can explain. The screams at night from the fight that can't be won. How can one carry such pain that no one knows about.
The fantastical planets in Star Wars preceded our discovery of real planets outside our solar system…but fiction isn’t too far from the facts. When we send our spacecraft into the solar system and point our telescopes beyond, we often see things that seem taken right out of the Star Wars universe.
Saturn’s moon, Mimas, has become known as the “Death Star” moon because of how its 80-mile wide Herschel crater creates a resemblance to the Imperial battle station, especially when seen in this view from our Cassini spacecraft.
The most recently revealed exoplanet dubbed as Earth’s bigger, older cousin, Kepler-452b, might make a good stand-in for Coruscant — the high tech world seen in several Star Wars films whose surface is encased in a single, globe-spanning city. Kepler-452b belongs to a star system 1.5 billion years older than Earth’s! That would give any technologically adept species more than a billion-year jump ahead of us.
At 3,600 degrees Fahrenheit, CoRoT-7B is a HOT planet. Discovered in 2010 with France’s CoRoT satellite, it’s some 480 light-years away, and has a diameter 70% larger than Earth’s, with nearly five times the mass. Possibly the boiled-down remnant of a Saturn-sized planet, its orbit is so tight that its star looms much larger in its sky than our sun appears to us, keeping its sun-facing surface molten!
Luke Skywalker’s home planet, Tatooine, is said to possess a harsh, desert environment, swept by sandstorms as it roasts under the glare of twin suns. Real exoplanets in the thrall of two or more suns are even harsher! Kepler-16b was the Kepler telescope’s first discovery of a planet in a “circumbinary” orbit (a.k.a, circling both stars, as opposed to just one, in a double star system). This planet, however, is likely cold, about the size of Saturn, and gaseous, though partly composed of rock.
Fictional Hoth is a frozen tundra that briefly serves as a base for the hidden Rebel Alliance. It’s also the nickname of real exoplanet OGLE-2005-BLG-390, a cold super-Earth whose surface temperature clocks in at minus 364 degrees Fahrenheit.
Kepler-22b, analog to the Star Wars planet Kamino…which was the birthplace of the army of clone soldiers, is a super-Earth that could be covered in a super ocean. The jury is still out on Kepler-22b’s true nature; at 2.4 times Earth’s radius, it might even be gaseous. But if the ocean world idea turns out to be right, we can envision a physically plausible Kamino-like planet.
Gas giants of all stripes populate the real exoplanet universe; in Star Wars, a gas giant called Bespin is home to a “Cloud City” actively involved in atmospheric mining. Mining the atmospheres of giant gas planets is a staple of science fiction. We too have examined the question, and found that gases such as helium-3 and hydrogen could theoretically be extracted from the atmospheres of Uranus and Neptune.
Endor, the forested realm of the Ewoks, orbits a gas giant. Exomoon detection is still in its infancy for scientists on Earth. However, a possible exomoon (a moon circling a distant planet) was observed in 2014 via microlensing. It will remain unconfirmed, however, since each microlensing event can be seen only once.
Make sure to follow us on Tumblr for your regular dose of space: http://nasa.tumblr.com
Half of seeming clever is keeping your mouth shut at the right times.
Patrick Rothfuss (via quotemadness)
Fascinating knowledge, I learn something everyday.
You can see an owl’s eyeball through it’s ear.
Star Wars!
Clever
(Source)
Hate isn’t the most dangerous thing, he’d said. Indifference is.
Lauren Oliver, Delirium (via booksqouted)
Very true, people will kill you... Or make you beg for it by the time they're done ridiculing you.
It' d be an honor for my tombstone to say, "Here Lies Dead Space". -Sándra Medley.
Takes place inside the mitochondrial matrix HOWEVER succinate dehydrogenase is bound to the membrane and so this step occurs there. It is the only enzyme that participates in both the krebs cycle and the electron transport chain.
Two molecules of carbon dioxide are given off
One molecule of ATP is formed (it’s not, it’s GTP which is considered an ATP equivalent - your examiner may or may not like this)
Three molecules of NAD+ are combined with hydrogen (NAD+ → NADH)
One molecule of FAD+ combines with hydrogen (FAD+ → FADH)
Because two acetyl-CoA molecules are produced from each glucose molecule, two cycles are required per glucose molecule. Therefore, at the end of two cycles, the products are: two ATP(GTP), six NADH2, two FADH2 and four CO2.
Can———-Citrate
Adam———-(cis)-Aconitate
Intrigue———-Isocitrate
A———-alpha-ketoglutarate
Super———-Succinyl-CoA
Sexy———-Succinate
Foxy———-Fumarate
Mama———-Malate
Ok!———-Oxaloacetate
(i stole this mnemonic from here)
Here’s a gap-fill game for practise
note: Citrate= Citric Acid, Fumarate= Fumaric Acid, etc…
For MOST of the enzymes, the name of the enzyme consist of the molecules it modifies(the molecule directly before it, and the function the molecule carries out)
If you’ve learnt the above order then you can use this to apply that
So———-citrate Synthetase
At———-Aconitase
Another———-Aconitase
Dance———-isocitrate Dehydrogenase
Devon———-alpha-ketoglutarate Dehydrogenase
Sipped———-Succinyl-CoA Synthetase
Down———-Succinate Dehydrogenase
Five———-Fumarase
Drinks———-malate Dehydrogenase
3 out of the 4 dehydrogenase enzymes will remove 2H (and an electron) from the molecule an put it onto a NAD;
remove a CO2;
and NAD –> NADH2.
The only exception is Succinate Dehydrogenase which places 2H atoms on an FAD molecule instead of an NAD
How can I ever appreciate happiness again when you were the first and only to bring me this experience in ten years. Now any form of happiness felt is followed by depression and regret.
Please understand, this isn't just goodbye this is I can't stand you.
Am I invisible or just matter the least to you.
I want to know you. You seem like someone worth knowing. Every day I feel like I’m surrounded by people with hard edges and sour faces but I get the sense that you’re different. Too often people seem to think that they have the answers to everything. Their faces are trapped in permascowls and they can’t be bothered with anything besides their own narcissism. You aren’t like that. You still ask questions. You’re still looking for the answers.
Ryan O'Connell (via quotemadness)
I thought I found this unique person to be around me as a friend...
My gosh, I need to make me one. I never thought of it this way. Only thing missing is the shrimp sauce!!!
Food mashups are right up there with music mashups as our favorite kinds of mashups. In the past, we’ve brought you things like the egg waffle cone. Now, meet your new best friend, the sushi burger. The concept behind it is a pretty simple one: You take rice as the bun and put sushi quality fish or other ingredients where the burger meat goes. But the execution is finger-kissing good. Sushi burgers are all over Instagram. Look at them. (Source)
Love lasts about seven years. That’s how long it takes for the cells of the body to totally replace themselves.
Françoise Sagan (via quotemadness)
And it's all in how you mix the two, and it starts just where the light exists. It's a feeling that you cannot miss and it burns a hole through everyone that feels it. Should've done something but I've done it enough by the way your hands are shaking, rather waste some time with you.
Chewbacca and I!
Start a fight I won't win. All in all I'm no good, I don't cry like I should when love does in the end, for I find what lies beneath your sick twisted mind. You're so unkind, I will always be here for the rest of my life.
via: The Insect World
Chewbacca!
Here’s a death match between a T-cell (immune system) and a cancer cell. I know which one I’m rooting for. (Source)
When there’s something on my mind, it takes my concentration.
Just wanna lay it on the line, avoid all confrontation. I’ve had enough of this circulation.
My nice Google theme.
Theme for facebook, before it was popular lol .. it’ll be public as soon as I can figure the code placement out.
Dear pain, its been a long time. Remember when you were holding me tight. I would stay awake with you all night. Dear shame, I was safe in your arms. You were there when it all fell apart. Go ahead but a target on my head, you can fire. Everything that we had together was a lie. You don't own me...
I wish.
You have to be sophisticated if you played this at the age of three.
Scientists Watch Activity of Newborn Brain Cells in Mice; Reveal they are Required for Memory
Columbia neuroscientists have described the activity of newly generated brain cells in awake mice—a process known as adult neurogenesis—and revealed the critical role these cells play in forming memories. The new research also offers clues as to what happens when the memory-encoding process goes awry.
This study, led by researchers at Columbia’s Mortimer B. Zuckerman Mind Brain Behavior Institute and Columbia University Medical Center (CUMC), was published in Neuron.
“Our approach allows us to compare the activity of newborn and mature cells in the brains of behaving animals,” said Attila Losonczy, MD, PhD, a principal investigator at Columbia’s Zuckerman Institute, assistant professor of neuroscience at CUMC and a senior author of the paper. “These findings could help scientists decipher the role that adult neurogenesis plays in both health and disease.”
Most brain cells are produced before birth, but a few select brain regions continue to grow new cells into adulthood. One such region is called the dentate gyrus, a tiny structure in the hippocampus, the brain’s headquarters for learning and memory. But because the dentate gyrus is so small, and buried so deeply within the brain, scientists have had difficulty studying it.
“One of the great unanswered questions in neuroscience is, why did nature decide to replenish cells in this region of the brain, but not others?” said Dr. Losonczy. “In this study, we developed sophisticated and refined methods to investigate this question more thoroughly than ever before.”
Earlier studies suggested that cells within the dentate gyrus, known as granule cells, allow the brain to distinguish between similar, yet different, environments. This process, known as pattern separation, is a key component of the brain’s internal GPS. It helps us remember where we parked the car this morning, versus where we parked two weeks ago, for example.
“Most granule cells are present in the dentate gyrus from birth, but a small percentage are the result of adult neurogenesis, which churns out fresh granule cells into adulthood,” said René Hen, PhD, professor of neuroscience and pharmacology (in psychiatry) at CUMC and a senior author of the paper. “We hypothesized that these so-called adult-born granule cells play a crucial role in pattern separation.”
Using a two-photon microscope, the researchers observed the activity of adult-born granule cells in the brains of mice as they walked along a treadmill. In order to induce the formation of new memories, this treadmill was lined with distinct textures and surrounded by different multisensory cues. The scientists were able to map how both types of granule cells—the new, adult-born cells as well as the old, mature cells—were involved in pattern separation.
“Other studies had been unable to image the dentate gyrus, let alone the individual cells that reside within it, at this level of detail,” said Mazen Kheirbek, PhD, the paper’s last author who completed this work while at Columbia. “Here, we were able to demonstrate that adult-born granule cells act differently than their mature neighbors, and determine why that difference is so critical.”
The difference, the researchers found, lies in the adult-born cells’ unique activity pattern. Shortly after they are produced, adult-born granule cells exhibit heightened excitability compared with their mature counterparts. But after six weeks, this activity drops off. The initial burst of excitability, the authors postulated, could be key to capturing the memories required for pattern separation.
To determine what happens when this process is disrupted, the researchers placed the mice in one environment and gave them a small footshock. Then, they introduced the animals to a second, safe, environment that was similar, yet distinct, from the first. Using optogenetics—a technique that uses laser light to manipulate specific brain cells—the scientists temporarily silenced the adult-born granule cells during exposure to the safe environment. A normal, healthy mouse could distinguish between the two settings and exhibited a fear response to the unfavorable environment. But to the mice with the silenced brain cells, both environments—both dangerous and safe—appeared the same, causing the mice to fear both environments.
“These findings reveal that adult-born granule cells are required not only to encode the memory of a new experience, but also to determine whether one experience is different from the next,” said Dr. Kheirbek. “The merging of memories, which is what we observed when the adult-born cells were silenced, is a key feature of a wide range of psychiatric conditions—from anxiety and mood disorders to post-traumatic stress disorder.”
“Indeed, the inability to discriminate between two distinct, but similar events—such as a gunshot versus a car backfiring—is often seen in these disorders,” said Dr. Hen. “Understanding how adult-born granule cells impact behavior in the living brain is an important step toward one day harnessing this process for therapeutic purposes.”