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1 year ago
Gonna Feel Very Accomplished Whenever I Look At This Page Now

Gonna feel very accomplished whenever I look at this page now


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is being a therapist reaaaallly worth it cause omg i have exams for the next 3 weeks and i am so ready to 🦢🤿

someone send a hit man to me pretty please i literally don’t know how to effectively revise i just look back at notes jot em down and hope for the bestšŸ˜•


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7 months ago

Cytochrome P450 Inducers & Inhibitors

The main ones can be remembered using "CRAP GPs spend all day on SICKFACES.COM".

Cytochrome P450 Inducers

These induce CYP450 activity, and thus reduce the concentration of drugs which are metabolised by this system.

Carbemazepine Rifampicin Alcohol (chronic use) Phenytoin Griseofulvin Phenobarbitone Sulphonylureas, St John's Wort, Smoking

Also topiramate.

Cytochrome P450 Inhibitors

These inhibit CYP450 enzyme activity and thus increase the concentration of drugs which are metabolised by this system.

Sodium valproate Isoniazid Cimetidine Ketoconazole Fluconazole Alcohol (acute use), Amiodarone, Allopurinol Chloramphenicol Erythromycin Sulfonamides, SSRIs Ciprofloxacin Omeprazole Metronidazole

Also grapefruit, cranberry juice, diltiazem, verapamil, clarithromycin.

Common Interactions

Medications which commonly interact with CYP450 inhibitors and inducers are:

Warfarin

Phenytoin

Combined Oral Contraceptive Pill (COCP)

Theophylline

Corticosteroids

Tricyclic antidepressants

Statins

Lamotrigine

Midazolam


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8 months ago

Haemosiderin staining

"Haemosiderin staining" describes orange/red/brown skin hyperpigmentation caused by haemosiderin (an iron-containing pigment found in blood) leaking into the skin.

Causes:

Chronic venous insufficiency (in lower legs)

Skin inflammation

Trauma e.g. wound, fracture, surgery

Pigmented purpuric dermatoses

Haemochromatosis

Haemosiderin staining may be exacerbated by anticoagulant use as this increases extravasation (leakage) of red blood cells into the skin.

See an example here.


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1 year ago

Causes of drug-induced lupus

SHIP

Sulfasalazine & Sulfonamide Hydralazine Isoniazid Procainamide & Phenytoin

This is by no means a definitive list (they are many!) but these are some of the most common causes.


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1 year ago

Common ototoxic medications

"FAV Q&A"

Furosemide (and other loop diuretics) Aminoglycosides Vancomycin Quinine Aspirin


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1 year ago

Hypokalaemia ECG changes

U have no pot and you have no T but you have a long PR and a long QT

Low potassium causes:

U waves (small deflection immediately after T wave)

Flattened/inverted T waves

Prolonged PR interval

Apparent prolonged QT interval (due to fusion of T and U waves)

Also:

Increased P wave amplitude

Widespread ST depression


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2 years ago

Oedema - pitting vs non-pitting

Oedema is swelling due to excess fluids in tissues.

In pitting oedema, pressing on the affected area leaves an indentation (that persists after removing the pressure). In non-pitting oedema, the area feels firm to touch and does not form indentations.

Pitting oedema:

The excess fluid is mainly composed of water

Commonly caused by heart failure, venous insufficiency, or nephrotic syndrome

Non-pitting oedema:

The excess fluid consists of water WITH protein and salts

Usually indicates a condition of the thyroid / lymphatic system

Different types:

Lymphoedema is due to a build-up of lymphatic fluid (e.g. due to a tumour blocking lymphatic flow / after removal of lymph nodes).

Myxoedema occurs in hypothyroidism and often affected the pretibial or periorbital area.

Angioedema is localised swelling of the skin and is usually due to allergic reactions. It typically affects the face, tongue, larynx, abdomen, arms, and legs. When the larynx is affected, it may affect breathing, which is an emergency!

Lipoedema is when fat accumulates in subcutaneous tissues - it usually affects the legs/buttocks and almost exclusively occurs in postpubertal females (not the same as cellulite!)

If patients present with oedema, it's always important to test if it's pitting or non-pitting as this helps to determine the cause and correct treatment!


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2 years ago

Causes of Acute Pancreatitis

In the UK and US, the main causes are gallstones and alcohol.

Use the mnemonic 'I GET SMASHED':

Idiopathic

Gallstones

Ethanol

Trauma

Steroids

Mumps / Malignancy

Autoimmune

Scorpion stings

Hypercalcaemia / Hypertriglyceridaemia / Hypothermia

ERCP

Drugs (including azathioprine, mesalazine, bendroflumethiazide, furosemide, steroids, sodium valproate)


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3 years ago

Branches of external carotid artery

Some Anatomists Like F*cking, Others Prefer S & M

Superior thyroid artery

Ascending pharyngeal artery

Lingual artery

Facial artery

Occipital artery

Posterior auricular artery

Superficial temporal artery

Maxillary artery

The superior thyroid, ascending pharyngeal, lingual and facial arteries are ANTERIOR branches.

The occipital and posterior auricular arteries are POSTERIOR branches.

The superficial temporal and maxillary arteries are TERMINAL branches.

ā€œSome Anatomists Like F*cking, Others Prefer S & Mā€Ā 

is a mnemonic my professor just mentioned in class for the branches of the external carotid artery askjvb;askjbv;


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3 years ago

Cranial nerves mnemonic

On, on, on, they travelled and found Voldemort guarding very ancient horcruxes.

Olfactory, optic, oculomotor, trochlear, trigeminal, abducens, facial, vestibulocochlear, glossopharyngeal, vagus, accessory, hypoglossal.

On - Olfactory nerve (CN I)

On - Optic nerve (CN II)

On - Oculomotor nerve (CN III)

They - Trochlear nerve (CN IV)

Travelled - Trigeminal nerve (CN V)

And - Abducens nerve (CN VI)

Found - Facial nerve (CN VII)

Voldermort - Vestibulocochlear nerve (CN VIII)

Guarding - Glossopharyngeal nerve (CN IX)

Very - Vagus nerve (CN X)

Ancient - Accessory nerve (CN XI)

Horcruxes - Hypoglossal nerve (CN XII)


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3 years ago

clearance = (urine concentration x urine volume passed over time) / plasma concentration

the only useful thing my prof ever taught me for the renal physiology portion of my physiology course is that clearance is calculated by the equation ā€œpissing under the sunā€ ( C = UV/P)


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3 years ago

Distribution of calcium in the body

Bone calcium (99%)

Ca^2+ and PO4^3+ form hydroxyapatite

Plasma calcium

Diffusible pool

~50% of plasma calcium is free/unbound ionic Ca2+ (physiologically important form)

~10% of plasma calcium is complexed with small molecular weight compounds (citrate, phosphate)

Non-diffusible pool

~40% of plasma calcium is bound to calcium-binding proteins and plasma proteins (albumin)

The body utilises plasma albumin-bound calcium as a circulating reserve


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3 years ago

Basic pharmacology of neuromuscular junction

ACh acts on N2 receptors (ligand-gated Na+/K+ receptors)

Block Na+ channels that propagate nerve impulse - local anaesthetics (lidocaine), tetrodotoxin

Inhibit ACh release - tetanus toxin, botulinum toxin

Competitive antagonists - vecuronium

N2 agonists - suxamethonium

Flaccid paralysis

Only cleared by plasma cholinesterase

Reversible anticholinesterases - edrophonium, neostigmine, physostigmine

Block activity of AChE

Diagnose and treat myasthenia gravis and treat glaucoma respectively

Irreversible anticholinesterases - organophosphates (pesticides, nerve gases)

Long-lived flaccid paralysis

Treat with pralidoxime within 10 minutes - cleaves OP-AChE complex


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3 years ago

Management of acute MI

Reduce anginal pain

Morphine (+ anti-emetic)

Oxygen

Nitrate

Initiate reperfusion

Anti-platelet (aspirin, clopidogrel)

Thrombolytic (rtPA)

Primary angioplasty (PTCA)

Anticoagulant (heparin)

Protect myocardium

Beta-blocker

ACE inhibitor

Secondary prevention

Aspirin

Lipid-lowering (statin)

Lifestyle

Helpful Mnemonic Foe MI Treatment.

Helpful mnemonic foe MI treatment.


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3 years ago

Carpal bones mnemonic

So Long Till Pinky, Here Comes The Thumb

Scaphoid

Lunate

Triquetrum

Pisiform

Hamate

Capitate

Trapezoid

Trapezium

(going anti-clockwise in this diagram)

Carpal Bones Mnemonic

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3 years ago

Can - Citrate

I - Isocitrate

Keep - α-Ketoglutarate

Selling - Succinyl-CoA

Sex - Succinate

For - Fumarate

Money - Malate

Officer - Oxaloacetate

image

oh we are starting my favorite topic in biochemistry the tca cycle because whenever someone’s like :( it’s so hard to remember the intermediates :( i get to tell them about Can I Keep Selling Sex For Money Officer


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1 week ago

how i manifested (+revised) my dream body ą±Øą§Ž

How I Manifested (+revised) My Dream Body ą±Øą§Ž
How I Manifested (+revised) My Dream Body ą±Øą§Ž

This is my first post on my new account, though I am NOT new to the law and NOT new to loablr either. This post is specifically about how I manifested my dream body instantly with no technique besides knowing :)

How I Manifested (+revised) My Dream Body ą±Øą§Ž
How I Manifested (+revised) My Dream Body ą±Øą§Ž

PART ONE - the old story

In the old story, I was so fixated on my body and my weight all of the time, I was tracking my calories and weighing myself and my food obsessively and constantly gaining and losing weight. Back then, my beliefs were that 1) Excess food causes weight gain, 2) If I don't track my food and weigh myself, I will become too fat/skinny, and 3) There is something wrong with my body, and I need to diet/exercise to fix it.

Noticing these beliefs were key to changing the way I viewed food and my body, and therefore changing how I knew food to effect me and how I knew my body to be.

When I was overweight, I knew my body was too big, I knew I was eating too much, I knew excess calories made me gain weight. When I was underweight, I knew I had no appetite, I knew I was too bony, I knew that exercise makes you gain muscle which is why I had none, etc. I had to identify the limiting beliefs that made me know my body was a certain way.

How I Manifested (+revised) My Dream Body ą±Øą§Ž
How I Manifested (+revised) My Dream Body ą±Øą§Ž

PART TWO - writing the new story

Once I identified the beliefs that were holding me back and kept me from my goals ("I know I eat too much, even if I affirm I'm skinny, I'm still going to gain weight."), I could then change them. I wrote down a list of these beliefs, like I did above, and came up with reversals. For example;

"I overeat, so I will gain weight" -> "Calories aren't even real, so I can eat whatever I want and stay the same weight."

"I eat junk food, so I'll never be skinny" -> "I love how fast my metabolism is, I can eat junk all day and still stay so skinny." or "Junk food is just like other foods. Raspberries can't make me fat so neither can hamburgers."

"I don't exercise enough to be toned" -> "It's crazy how I'm naturally so toned and fit without trying."

The key for me was changing key beliefs that kept me dieting and exercising to lose weight, to sever the tie between calories consumed and weight, and hours exercising and muscles. These are limiting beliefs. We literally create our reality. Not ice cream, not soda and chips, none of that can overcome YOU as a divine creator. It sounds silly when you spell it out like that, doesn't it?

How I Manifested (+revised) My Dream Body ą±Øą§Ž
How I Manifested (+revised) My Dream Body ą±Øą§Ž

PART THREE - how i did it

Okay, now we understand that the secret is to change the rules of our own reality to allow us to know a higher truth (my higher truth? I am a skinny legend). So how do we put this into practice?

All you have to do is know. You set these rules, so you know they are true, reality is bound to them. You must know you are successful, know that reality is in the 4d, and feel truly satisfied in that realm. You can do this using whatever method you need to, but personally, I just knew deep within me that I was my ideal weight, and that nothing could change that, that is simply the reality, that is simply the way things are. I thought about old pictures I took of myself, and remembered how skinny I looked in them, I thought about the last time I saw my friends and how much littler they said I'd gotten, I thought about the last time I stood on the scale and how it read the exact weight I knew myself to be. And I just knew, deep within me, that was simply how things were.

And the last step, for me, was to feel truly joyful at this realization. To feel satisfied it came into fruition. Without seeking confirmation, because I already KNEW.

And what do you know? Pictures of myself in my phone from weeks ago, they were my ideal body. The girl I saw in the mirror when I stood up from my meditation? She had my ideal body. My clothes? XS and S, all of them. I had revised my ideal body all the way back to the day I bought them. And confirmed this by checking pictures I took in the dressing room.

I'm telling you right now it is possible if you know in your heart you've always had your desire. It's always been fulfilled within you. You make the rules because you are a divine creator. Nothing outside of you can change what you know to be true.

That's all for now ą±Øą§Ž


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1 week ago

how i revised my boyfriend’s mother’s death

How I Revised My Boyfriend’s Mother’s Death
How I Revised My Boyfriend’s Mother’s Death
How I Revised My Boyfriend’s Mother’s Death

a little backstory

— for the sake of privacy, we’re gonna say my boyfriend’s mother’s name is kay

kay’s ā€œdeathā€ was caused by a car accident (wasn’t her fault) and she later passed in the hospital. this all happened in new york, and my boyfriend and i live in georgia. but about a 2 days after we found out, we flew out there.

my bf and his mom were super close so that loss was a lot on him. he started burying himself in the gym, sleep, work etc & eventually he became really depressed. he would not get up out of bed and i could not take that. that was when i decided to revise her death, and this was like a week after she passed.

How I Revised My Boyfriend’s Mother’s Death

the moment i learned she was dead, i naturally entered the state of loss. so, i simply and quickly went over what state of mind i was currently in, and what state of mind i needed to be in.

now y’all know i love meditating <3 so ofc i meditated. the one i used is by edward art, i believe i’ve mentioned it before. but here’s the link šŸ˜ŒšŸ’˜

so yeah after this meditation i had completely satisfied my imagination, i had a great feeling of serenity, and i was in the state of the wish fulfilled. + i let go of any need to control the 3d.

— reminder: don’t look at your 3d as something to change. things change when they change in consciousness/imagination. if you wanna manifest something, don’t point out your current circumstance as something that you need to change. be cool and fulfill it in imagination;)

— also sn: my boyfriend knows about the law but he doesn’t necessarily study or consciously use it. so, i didn’t tell him i was revising his mom’s death.

— and i had to continue to act like his mom was actually dead when i was around him, even tho at this point kay was 100% alive in imagination.

How I Revised My Boyfriend’s Mother’s Death

so in the morning, i would wake up and assume the state of fulfillment. throughout the day, when i would go check on my boyfriend, he always expressed his feelings, how i could help, and new ways he was trying to cope. honestly, seeing him so hurt and confused hurt me. and throughout this, one of the few things i always reminded myself was that, i’m not my emotions and i’m my thoughts, and neither of those things matter (in terms of manifesting).

another thing i always reminded myself of was the fact that i’m god, BUT i’m also human. so, the ā€˜god me’ was relaxed & satisfied. the god in me also didn’t have a hurting boyfriend with a dead mom. but the ā€˜human me’ did and he needed my comfort.

so that’s what i did, i comforted him because he was grieving the death of his mother. so what? i’m human, and i have human decency so ima comfort my baby.

HOWEVER, i didn’t attach myself to that (accept it). i didn’t look at me comforting him as ā€œhis mom’s dead and that’s finalā€, i just did it because he’s my bf and he’s hurt. but i still maintained fulfillment in imagination.

How I Revised My Boyfriend’s Mother’s Death

— i talk about this more in depth here. but basically the post acknowledges that yes, you’re god, but you’re also still human and you have a human life to respond to. so do that, respond to your life (when necessary) while simultaneously fulfilling the inner man.

as long as you continue to return to the state and fulfill SELF, you will manifest whatever it is you’ve fulfilled.

How I Revised My Boyfriend’s Mother’s Death

when it manifested

the night before it manifested, my bfs dad asked everyone (the family) over for brunch. just so everyone could be together during rough times and whatnot.

the next morning when we woke up, my bf.. it was like he completely reverted; he just went back to his regular self. i made sure to take a mental note of it.

as we were driving to his dads house he was acting very normal. all that pain, hurt, etc was not there. his whole energy was different. then what really got me was when we had got to a red light. he said ā€œi already know my moms threw down, i wonder what she cookedā€ā€¦ā€¦ā€¦.and i’m like, i know i’m not trippin. just went along with it and agreed with him cause what was i supposed to do lol😭?

so we pull up to the house and get to the door, and one of his brothers opened it. as we’re saying hi and walking further into the house we start smelling food and my bf goes ā€œYUP! I KNEW IT!!ā€

then he walks into the kitchen and says ā€œhey ma watchu in here cooking? it smells goodā€ā€¦ā€¦. and his mom was literally standing there smiling before she gave him a hug.

this all happened naturally by the way. it was like… she never diedšŸ˜‚šŸ˜‚ the power of revision yall!

anyways the whole afternoon went by like nothing ever happened.

i honestly thought it was pretty funny. knowing how they used to interact with each other while they were grieving kay’s death vs now was hilarious. and what makes it funnier is they never knew and never will šŸ˜‚šŸ˜‚šŸ˜‚

How I Revised My Boyfriend’s Mother’s Death

so there y’all have it, how i revised my boyfriend’s mother’s death. sorry i made y’all wait so long:) i literally got so demotivated while trying to type this.

feel free to ask questions cause ik yall got somešŸ˜©šŸ˜‚ love y’all šŸ«¶šŸ¾


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