West Palm Beach FL (SPX) Jun 18, 2018 Aerojet Rocketdyne recently achieved a significant milestone by successfully completing a series of hot-fire tests of an advanced, next-generation RL10 engine thrust chamber design that was built almost entirely using additive manufacturing; commonly known as 3-D printing. “This recent series of hot-fire tests conducted under our RL10C-X development program demonstrated the large-scale add Full article
Biggest Ferris wheel ever: the Jupiter Eye
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CRISP(ie)R news than anything!
A powerful technique for editing genomes is now more precise. By tweaking an enzyme, researchers have reduced the error rate for the technique, known as CRISPR–Cas9 — in some cases to undetectable levels, they report on 6 January in Nature1.
Researchers use CRISPR–Cas9 to make precise changes to genomes that remove or edit a faulty gene. It has worked on nearly every creature on which they have tested it, including human embryos.
The technique relies on an enzyme called Cas9, that uses a ‘guide RNA’ molecule to home in on its target DNA. Cas9 cuts the DNA at that site, and the cell’s natural DNA repair machinery then takes over to mend the cut — deleting a short fragment of DNA or stitching in a new sequence in the process.
But the technology is not infallible: sometimes the Cas9 enzyme creates unwanted mutations. As CRISPR inches out of the laboratory and towards the clinic — with debates raging overwhether it should be deployed in embryos — researchers have pushed to reduce the error rate.
The latest study moves the field closer to that goal, says lead author Keith Joung, a pathologist at Massachusetts General Hospital in Boston. “This is a significant move forward,” he says. “We can very much reduce the probability of off-targets.”
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Thats amazing news :O
A team of researchers at Huazhong University of Science and Technology has developed a silk protein-based gel that they claim allows for skin healing without scarring. In their paper published in the journal Biomaterials Science, the group describes their gel and how well it works.
Scarring due to a skin injury is not just unsightly—for many, it can also be a painful reminder of a wound. For these reasons, scientists have sought a way to heal wounds without scarring. In this new effort, the team in China claims to have found such a solution—a sericin hydrogel.
The gel used by the researchers was based on a silk protein—the researchers extracted sericin from silk fibers and then used a UV light and a photoinitiator to cross-link the protein chains. The result was a gel that adhered well to cells and did not trigger much of an immune response. The researchers note that it also has adjustable mechanical properties. They explain that the gel allows for scar-free healing by inhibiting inflammation and by promoting the development of new blood vessels. It was also found to regulate TGF-β growth factors, which resulted in stem cells being routed to the injury site allowing new skin to develop, rather than scar tissue.
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On November 9, 1967, the uncrewed Apollo 4 test flight made a great ellipse around Earth as a test of the translunar motors and of the high speed entry required of a crewed flight returning from the Moon. https://go.nasa.gov/2zybcxC
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The Hydrogen Atom
Australia’s national science agency CSIRO has identified a new gene that plays a critical role in regulating the body’s immune response to infection and disease.
The discovery could lead to the development of new treatments for influenza, arthritis and even cancer.
The gene, called C6orf106 or “C6”, controls the production of proteins involved in infectious diseases, cancer and diabetes. The gene has existed for 500 million years, but its potential is only now understood.
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Vandenberg AFB CA (AFP) May 05, 2018 NASA on Saturday blasted off its latest Mars lander, InSight, designed to perch on the surface and listen for “Marsquakes” ahead of eventual human missions to explore the Red Planet. “Three, two, one, liftoff!” said a NASA commentator as the spacecraft launched on a dark, foggy morning atop an Atlas V rocket at 4:05 am Pacific time (1105 GMT) from Vandenberg Air Force Base in California, m Full article