Side Effects Of Drugs Commonly Given To The Elderly

CAMP test for the identification of Streptococcus agalactiae (group B). 

(A) Streptococcus (group B) shows a positive CAMP reaction arrow-shaped zone of enhanced hemolysis .

(B) Streptococcus pyogenes (group A) shows a negative reaction when inoculated at a right angle to

© Staphylococcus aureus.

Another Harry Potter Mnemonic (yayyy!!!)

So, whenever I read about this fungi Sporothrix schenckii I think about Bellatrix Lestrange… geti it? 

Sporothrix - Bellatrix

That evil deatheater that killed Sirius Black. But they actually got it wrong in the movie, she doesn’t “Avada Kedavra” him, she just knocked him through that veil where you could hear death people….

Ok, enough with the Harry Potter fact.

To diagnose an infection from Sporothrix schenckii, you have to see this cigar shaped yeasts (from the pus of the lesions), which are the tissue form of the fungi. 

So to remember this, just picture:

“Bellatrix Lestrange smoking a cigar”

(Sporothrix: cigar shaped yeast in pus)

Difference between Blood Agar and Chocolate Agar

Hi everyone!

I’ll tell you in short about Nutrient agar first

It is a simple basal medium used for growth of common pathogens

It constitutes peptone water, meat extract and agar

Difference between Blood Agar and Chocolate Agar

What is common between Blood agar and Chocolate agar?

Both are enriched media

Used for the growth of Gram positive cocci and fastidious organisms like Neisseria & Haemophilus species

Can be used to indicate hemolysis

What are fastidious organisms?

They require specialized environments due to complex nutritional requirement

What is the difference between Blood agar and Chocolate agar?

The difference lies in how the media are made

How is Blood agar made?

Nutrient agar is sterilized by autoclave, cooled to 50°C and sterile sheep blood (5-10%) is added gradually and poured into plates

How is Chocolate agar made?

Nutrient agar is sterilized by autoclave, cooled to 75-80°C and sterile sheep blood (5-10%) is added gradually and poured into plates

How is the difference in temperature significant?

Certain organisms such as Haemophilus species require V factor for growth (complex nutritional requirement)

Factor V is present in blood but it is present inside the red blood cells (RBC)

These organisms can not utilize V factor which is trapped inside the RBC’s in Blood agar

When Blood agar is heated to 80-90°C for a few minutes (boiled blood agar), the V factor is released from within the erythrocytes and made available to the organism for utilization

Some strains of Neisseriae and Diphtheroids require V factor too

That’s why these media are superior to plain Blood agar for growing organisms requiring V factor

What is V fatcor?

V fatcor is a coenzyme, Nicotinamide Adenine Dinucleotide (NAD) or Nicotinamide Adenine Dinucleotide Phosphate (NADP) which acts as a hydrogen acceptor in the metabolism of cell

So to conclude, Chocolate agar is a type of blood agar in which the blood cells have been lysed by heating for growing fastidious organisms :)

Did you know?

Modified Thayer Martin is a type of chocolate agar which contains antibiotics (Vancomycin, Nystatin & Colistin) to suppress growth of other bacteria and promote growth of  N gonorrhoeae

*phew* That’s all for today!

The image is my first photoshop work on the site, hope you like it =D

Just to remind you guys, Chocolate agar contains no chocolate, they simply named it after the yummy color :P

-IkaN

Hi optom! I'm very new to the studyblr community and it's my first term of university. I was a straight A student in high school and i am not performing well in my classes. In fact... I'm doing terribly. About a B to B- average. I know I'm probably not the first to go through so I've been trying to find posts that help students cope with this. Resources. Helpful tips. Is there a tag you can recommend? Any posts that you've encountered/wrote that I could peruse? Thank you very much for any help!

Hey there, thanks for asking. This is actually a very common problem experienced by people as they progress from high school to university. 

The problem is that mediocre study techniques and a combination of natural ability may have gotten you straight As whilst in high school, but it’s just not going to cut it in university. Cracking down on yourself and sitting down for more hours isn’t going to make your grades much better; it’s just doing more of the same mediocre studying. 

So you basically need to read up on good studying techniques and actually apply them to your studies. 

Everything You Need to Cover To Succeed As A Student

I actually have a web directory of all my study tips which already lists all these links.

So because the problem you have at its base is most likely that you’re using high school level techniques to tackle university-level problems, you’ll need to find resources on all areas related to good studying. For some of these areas, I have a related post, but for the more generalised topics like procrastination, I haven’t yet put one out because if I do, I want to be certain that the post will be unique, useful and practical. 

Without further ado, here’s a list of all the tags/areas you should work through and evaluate whether you need to change your current study habits if you want to be a 4.0/HD student at university. 

Firstly, have a read of my recent answer about 20 Things You Can Do To Prepare for University, and click through to any of the parts of my 15-Part University 101 Series. 

Time management

Organisation (see Part 3 Studying and Part 8 Four Secrets from University and Part 11 Adapting to Uni Studying which covers how you can manage university workloads on the whole and specific changes to your studies you should make)

Motivation

Discipline / Staying Focused

Procrastination (see post by @samsstudygram​)

Study Methods (I’ve got one on the Blank Paper Method and the Cornell Method)

Exams (I’ve got a multi-part series in the works)

Study Materials (see Part 2 of my University Series for some tips)

Studying from Textbooks (see Part 12 How To Study From Textbooks in Uni which deals with this specifically)

Self Care (you can see my tag here of my own + useful curated posts)

Spaced Repetition (use Anki!)

Study Space (I have a masterpost with tips here)

Hope that helps! If you have a specific question about any areas then let me know! 

Leukocyes (WBCs) & Defence

A summary

Neutrophils -  non-specific defence against bacteria and fungi

Eosinophils -Defence against parasites; dampen allergic response

Basophils  - Anaphylactic & inflammation response

Monocytes - Mature into macrophages, engulf foreign substances;  remove aged RBCs and other debris

Lymphocyes - Recognise antigens, various roles

Medically Important Fungi

Listeria with tumbling motility (by Pathmass)

Listeria monocytogenes

Gram+, aerobic, motile rod, facultative intracellular, beta hemolytic on blood agar

Tumbling motility in broth (as seen in video)

Jet motility in cells by actin filament formation

Listeriolysin O (Beta hemolysin): pathogenic factor, facilitates it scape from phagosome before phagolysosome formation and “jets” into another cell.

Diseases:

Lysteriosis: asymptomatic or diarrhea. 

Lysteriosis in pregnant women septicimia, crosses placenta.

Granulomatosis infantisepticum: neonatal disease, in utero transmission, sepsis, diseminated granulomas and high mortality.

Neonatal sepsis and meningitis (3° most common cause) 2-3 weeks after birth (fecal exposure)

Septicemia and meningitis in immunocompromised pts

Meningitis in renal transplant pts, cancer pts

What is Acute or Subacute Bacterial Endocarditis?

Acute or Subacute Bacterial Endocarditis is an infection of the heart’s endocardium. The endocardium is the inner lining of the heart muscle, which also covers the heart valves. Bacterial Endocarditis can damage or even destroy your heart valves. The difference between acute and subacute bacterial endocarditis is acute bacterial endocarditis is a sudden onset, whereas subacute bacterial endocarditis is a gradual onset.

Acute endocarditis most often occurs when an aggressive species of skin bacteria, especially a staphylococcus (staph), enters the bloodstream and attacks a normal, undamaged heart valve. Once staph bacteria begin to multiply inside the heart, they may send small clumps of bacteria called septic emboli into the bloodstream to spread the infection to other organs, especially to the kidneys, lungs and brain. Intravenous (IV) drug users are at very high risk of acute endocarditis, because numerous needle punctures give aggressive staph bacteria many opportunities to enter the blood.If untreated, this form of endocarditis can be fatal in less than six weeks.

Subacute endocarditis is caused by one of the viridans group of streptococci (Streptococcus sanguis, mutans, mitis or milleri) that normally live in the mouth and throat. Streptococcus bovis or Streptococcus equinus also can cause subacute endocarditis, typically in patients who have some form of gastrointestinal cancer, usually colon cancer. Subacute endocarditis tends to involve heart valves that already are damaged in some way, and it usually is less likely to cause septic emboli than acute endocarditis. If untreated, subacute bacterial endocarditis can worsen for as long as one year before it is fatal.

Antibiotics: Protein Synthesis Inhibitors

Protein Synthesis

Formation of Initiation Complex (tRNA in P site)

aa incoorporation (tRNA in A site, aminoacyl-tRNA)

Formation of Peptide Bond (peptidyltransferase)

Translocation

MNEMONIC: “ALi  eSTá  Cuasi  MAL”

* Inhibit 1: “ALi”

A minoglycosides

Li nezolid

* Inhibit 2: “eSTá”

S treptogramins

T etracyclins

* Inhibit 3: “Cuasi”

C loramphenicol

* Inhibit 4:  "MAL"

M acrolides

A minoglycosides

L incosamides

[x]