ETC Shortcuts

This disease typically affects children because, well, kids are gross and have fewer inhibitions about sticking their poop hands in their mouth

Sketchy Medical on Enterobius vermicularis (via medschoolmanic)

Pizza heaven! Quick and easy! Recipe up on blog: www.studydiaryofamedstudent.wordpress.com

Bacterial strain X is resistant to Ampicillin and sensitive to Gentamycin. Bacterial strain Y is resistane to gentamycin and sensitive to Ampicillin. Bacterial strain X and Y are grown in mixed culture in medium without antibiotics, then the culture is plated on medium containing both ampicillin…

Passive Immunotherapy

Active immunotherapies:

Cytokines (TNFa IL-2, IFNs)

Cancer vaccines

tumour CTL and APC

DC priming

Passive immunotherapy:

Administration of monocolnal (clone derived asexually from a single individual or cell) antibodies which target either tumour-specific or over expressed antigens

Generally comprised of antibodies made outside of the body (in a lab)

administered to patients to provide immunity against a disease, or to help fight existing disease

do not stimulate a patient’s body to ‘actively’ respond to a disease the way a vaccine does

immunogen is given several times to induce a strong secondary response

blood serum contains many different antibodies to the immunogen

most immunogens have multiple antigenic epitopes 

each stimulates a different B cell clone/receptor –> polyclonal antibody (PAb) response 

Monoclonal antibody (mAb) therapy is the most widely used form of cancer immunotherapy. Monoclonal antibodies cannot be purified from a polyclonal sample and are derived from a single clone/specific for a single epitope.

Antibodies in cancer therapy:

Trigger immune system to attack cancer cells 

Block molecules that stop the immune system working (checkpoint inhibitors)

 Block signals telling cancer cells to divide 

Carry drugs or radiation to cancer cells

Checkpoint inhibitors

Immune system uses particular molecules to stop it being over activated and damaging healthy cells  - these are known as checkpoints

some cancers make high levels of checkpoint molecules to switch of immune system T cells which would normally attack cancer cells

examples of targets include CTLA-4, PD-1 and PD-L1 (programmed death ligand 1)

Blocking cell division signals 

Cancer cells often express large amounts of growth factor receptors on their surface –> rapid cell division when growth factors stimulate them

some monoclonal antibodies stop growth factor receptors working

either by blocking the signal or the receptor itself 

cancer no longer gets signal to divide

Carrying drugs/radiation

drugs or radioisotopes can be attached to monoclonal antibodies

the mAB binds to the cancer cell, delivering directly

known as conjugated MABs

Horizontal gene transfer

Hi, everyone!! I’ve had a studyblr for about a week now and have already met so many kind, supportive people. I couldn’t be more thankful. That said, I really wanted to give back to such an amazing community! So here’s my first printable for you! 

It includes:

a 5AM-10PM schedule (for my early hustlers)

‘Top 3 Priorities’ + ‘Can Wait’ categories

a ‘To-Do’ list

Daily Goals, Notes, Doodles

a water tracker (stay hydrated, friends!)

10 Good Things (reflect back on your day and jot down the little things that made you happy even if your day wasn’t the greatest)

They’re available for download in PDF and PNG formats + in pink, blue, yellow, and white! I’ve also made a grid and grid-less version! 

Grid

Blue: pdf / png Pink: pdf / png White: pdf / png Yellow: pdf / png

No Grid

Blue: pdf / png Pink: pdf / png White: pdf / png Yellow: pdf / png

And here’s a link to the entire folder on my DropBox!

Please tag me with #arystudies or mention me if you use these!! I’d love to see them in action. :’) I’m also really curious to see what you all think of them, so please let me know!! 

Be sure to check out my monthly calendars too!

Happy studying!  

Hello everyone, welcome to my latest 4-part series to help you land that job after uni! This series will cover what to do before, during, and after a job interview to ensure you leave a positive impression on the interviewers and hopefully help you cinch opportunities! Enjoy!

How To Set Your Career On The Right Path Before You Even Graduate! (Link) Part 2: During The Interview (Link) Part 3: After The Interview (Link)

Research the job position and company values. 

It is critical to tackle all the requirements in your cover letter as well as your resume, and to be able to answer questions in the interview in a way that highlights you have those values the company is seeking. Even if the company doesn’t have a public ad, research similar positions at different companies and read those job descriptions. Have situations you’ve dealt with in your arsenal for answering situational questions. 

Make sure your resume is updated perfectly. 

It’ll save you a lot of time if you just update your resume every time you start something new! Standard stuff: Use ‘clean’ standard fonts, white A4 paper, single sided, 2 cohesive colours max. Include at least the minimum components or a combination of them: the rough order should be:

Career Objective

Education

Relevant Experience (include key responsibilities and noteworthy performance points)

Extra-Curricular Activities (if relevant)

Skills

Referees (usually just write “available on request”)

Cold call!

This is how I got my first relevant job as an optical assistant, which in a way, led to my current position today. Even whilst I was working as an optical assistant, occasionally we would get a new hire if their resume seemed good and they interviewed well. 

Prepare for common interview questions. 

Have scenarios ready illustrating how you dealt with a difficult situation 

be patient, good things are coming your way :)

If you cannot grasp what I have just explained, you should just leave and study economics!

Microbiology professor, first lecture (via scienceprofessorquotes)

Side effects of drugs commonly given to the elderly

For sleep aid do not give barbituates or diphenhydramine (1st gen antihistamine). Instead, give Ramelteon.